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Fosravuconazole L-lysine ethanolate

CAS No. 914361-45-8

Fosravuconazole L-lysine ethanolate ( BMS-379224 L-lysine ethanolate; E-1224 L-lysine ethanolate )

Catalog No. M24954 CAS No. 914361-45-8

FosravuconazoleL-lysine ethanolate is a broad-spectrum antifungal agent. In Japan, it is approved for the treatment of onychomycosis, a fungal infection of the nail. It is a prodrug that is converted into ravuconazole.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 48 In Stock
5MG 68 In Stock
10MG 110 In Stock
25MG 215 In Stock
50MG 340 In Stock
100MG 560 In Stock
200MG 791 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Fosravuconazole L-lysine ethanolate
  • Note
    Research use only, not for human use.
  • Brief Description
    FosravuconazoleL-lysine ethanolate is a broad-spectrum antifungal agent. In Japan, it is approved for the treatment of onychomycosis, a fungal infection of the nail. It is a prodrug that is converted into ravuconazole.
  • Description
    FosravuconazoleL-lysine ethanolate is a broad-spectrum antifungal agent. In Japan, it is approved for the treatment of onychomycosis, a fungal infection of the nail. It is a prodrug that is converted into ravuconazole.
  • Synonyms
    BMS-379224 L-lysine ethanolate; E-1224 L-lysine ethanolate
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    914361-45-8
  • Formula Weight
    739.7
  • Molecular Formula
    C31H40F2N7O8PS
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:48mg/mL (64.89mM)
  • SMILES
    N#CC1=CC=C(C2=CSC([C@H](C)[C@@](OCOP(O)(O)=O)(C3=CC=C(F)C=C3F)CN4N=CN=C4)=N2)C=C1.CCO.N[C@H](C(O)=O)CCCCN
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Diniz LF, Mazzeti AL, Caldas IS, Ribeiro I, Bahia MT. Outcome of E1224-Benznidazole Combination Treatment for Infection with a Multidrug-Resistant Trypanosoma cruzi Strain in Mice. Antimicrob Agents Chemother. 2018;62(6):e00401-18. Published 2018 May 25. doi:10.1128/AAC.00401-18Watanabe S, Tsubouchi I, Okubo A. Efficacy and safety of fosravuconazole L-lysine ethanolate, a novel oral triazole antifungal agent, for the treatment of onychomycosis: A multicenter, double-blind, randomized phase III study. J Dermatol. 2018;45(10):1151-1159. doi:10.1111/1346-8138.14607
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